A biologist has developed a blood test for detecting a certain minor abnormality in infants. Obviously if you have blood samples from 100 children, you could find out which children are affected by running 100 separate tests. But mathematicians are never satisfied by the obvious answer. Keith Ball uses information theory to explain how to cut down the number of tests significantly, by pooling samples of blood.
Marcus du Sautoy begins a two part exploration of the greatest unsolved problem of mathematics: The Riemann Hypothesis. In the first part, we find out how the German mathematician Gauss, aged only 15, discovered the dice that Nature used to chose the primes.
Calculus is a collection of tools, such as differentiation and integration, for solving problems in mathematics which involve "rates of change" and "areas". In the first of two articles aimed specially at students meeting calculus for the first time, Chris Sangwin tells us about these tools - without doubt, the some of the most important in all of mathematics.
Not only are paper models of geometric shapes beautiful and intriguing, but they also allow us to visualise and understand some important geometric constructions. Konrad Polthier tells us about the gentle art of paper folding.
Combinatorial Game Theory is a powerful tool for analysing mathematical games. Lewis Dartnell explains how the technique can be used to analyse games such as Twentyone and Nim, and even some chess endgames.
Human beings are famously prone to error, and proof-readers are, after all, only human. But who picks up the errors a proof-reader misses? John D. Barrow challenges readers to estimate the errors that aren't found from the errors that are.