Plus Blog

March 4, 2009
Wednesday, March 04, 2009

What happened before the Big Bang?

It's official! The question that Plus readers would most like to have answered about the Universe is "What happened before the Big Bang?" In the first of seven online polls to celebrate the International Year of Astronomy 2009, the Big Bang question picked up 48% of your vote, followed by the questions "What is the future of the Universe?" with 14% and "When will we be able to live in space?" with 11%. Thanks to all of those who voted, and especially those who left the many intelligent comments.

We'll now try and find an answer to this question with the help of expert cosmologists and astronomers, and we'll publish our efforts in the middle of March. At the same time we will launch our second Universe poll, which will take into account the questions you posed in your comments. So keep an eye on our blog, or subscribe to our newsletter to receive regular email updates.

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posted by Plus @ 3:43 PM

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February 27, 2009
Friday, February 27, 2009

Bye bye finance, hello maths and science

We may be in a recession, but according to Gordon Brown, that's all the more reason to invest in science and maths education. In a speech in Oxford today, Brown pledged to increase the number of students taking maths A level from the current 56,000 to 86,000 in 2014, and to make sure that 90% of state schools teach physics, chemistry and biology as separate subjects, also by 2014. The measures are meant to help ensure Britain's future competitiveness, and ease its over-dependence on financial services, which have got us into this mess in the first place. Some of the losers of the recession, those who have lost their jobs but have maths, science and IT degrees, are to be encouraged and supported to take up teaching, to tackle the lack of specialist teachers in these subjects. Brown also pledged to encourage a positive public debate about science in order to improve the public's understanding of its role in society.

Find out more with BBC News and in The Guardian articles Gordon Brown announces plan to boost school science and Brown pledges support for redundant graduates to retrain as science teachers.

posted by Plus @ 4:25 PM

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February 24, 2009
Tuesday, February 24, 2009

Geneticists are usually concerned with picking apart the individual genes that make up a genome, but now two biochemical engineers from the University of Wisconsin Madison have decided to re-assemble all the pieces and give them a good shake. They found that it's not just the genes themselves, but also the way in which they are organised within the genome, that determine the characteristics of an organism.

Read more...

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posted by Plus @ 12:02 PM

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At 2:48 PM, Blogger Cassandra said...

This type of permutation is exactly what keeps us "interesting" despite greater evidence of mechanistic implementation and structure in biology. Even given the fact that "not all permutations are equally likely" the variation in time and space and the Hilbert spaces of DNA, neural nets and life threads are still enormously re-combinatorial.

 
February 24, 2009
Tuesday, February 24, 2009

Life's an algorithm

It's not often that maths makes it into the mainstream media, and when it does, it's usually a very specific bit of maths — a statistical result or a certain application — that's being examined. An article published yesterday on the Guardian website makes a nice exception. It explores how maths underlies almost every aspect of modern life, from traffic lights to iTunes. Thank you, Guardian!

You can find out more about some of the topics mentioned in the article on Plus:

posted by Plus @ 11:45 AM

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February 20, 2009
Friday, February 20, 2009

We're doomed, say scientists

Sometimes a boring story can become a lot more interesting if you do some skilled number juggling. This is what seems to have happened in an article in The Daily Telegraph, which claims that 90% of us carry a gene which increases the risk of high blood pressure by 18%. And high blood pressure is of course linked to dreaded killers like stroke and heart disease.

In his Understanding Uncertainty blog David Spiegelhalter traces the story back to a paper in Nature Genetics. The authors of the paper investigate three gene variants that can occur in the human genome. Two of them are rare, only about 10% of the population carry them, while the third is present in 90% of the population. The authors show that the gene variants are associated to proteins called natriuretic peptides, which are linked to blood pressure (this is the main point of the paper, since such a genetic connection had never before been found). The two rarer gene variants, according to the paper, reduce the risk of high blood pressure by 15%. The phrase "18% increased risk of high blood pressure" appears nowhere in the paper. Rather it's the result of some creative accounting on the part of someone operating in the media chain which links the actual paper to the final article in The Daily Telegraph. Here's how it's done:

Say that the risk of high blood pressure for someone carrying the more common gene variant is x. Now the 15% decrease associated to the two less common variants takes this down to 0.85x. To get back to x, we need to add 0.15x, and this is exactly 17.647% of 0.85x — hence the claim of an 18% increase in risk.

The calculation is undoubtedly correct, but it puts a spin on the story. Rather than taking the common case as a base line and talking about the risk reduction associated to the less common cases, it does things the other way around. This is in stark contrast to the paper's authors own turn of phrase, which links the rarer variants to risk reduction, but says that the common variant "was not significantly associated with either systolic or diastolic blood pressure." It's a bit like noting that some people live to 110 and then complaining that most of us die prematurely. "This is a masterful piece of re-framing of the evidence," says Spiegelhalter on his blog. "Not exactly wrong, but definitely changing the story. Just like a change from 98% to 96% in a survival rate seems a lot more innocuous than a doubling of the mortality rate from 2% to 4%."

If you'd like to find out more about risk and uncertainty, visit the Understanding Uncertainty website, or read Spiegelhalter's column in Plus.

To find out more about simple number smoke screens, read the Plus article The tiger that isn't.

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posted by Plus @ 1:01 PM

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February 18, 2009
Wednesday, February 18, 2009

Finally, recognition for string theory

stringtherry.jpg
Image from icanhascheezburger.com

Better than a celebrity endorsement, string theory now has a feline spokeskitten! (Thanks Oli for letting us know the good news!)

Why not educate your animal friends with these Plus articles:

posted by Plus @ 12:07 PM

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