This is an excerpt from Stephen Hawking's address to his 70th birthday symposium which took place on 8th January 2011 in Cambridge.

We have all become more aware of the dangers of influenza this year, but why is it so dangerous? Julia Gog explains that the unusual structure of the influenza genome can lead to dangerous evolutionary jumps, and how mathematics is helping to understand how the virus replicates.

In 1979 decorating work in a house in Vienna revealed a set of medieval frescoes depicting a cycle of songs by a 13th century poet, who was particularly fond of satirising the erotic relationships between knights and peasant maidens. The frescoes are of great historical significance, but they are badly damaged. In this article Carola Schönlieb explores how mathematicians use the heat equation to fill in the gaps.

As anyone starting out knows, the violin is a difficult instrument. It takes time before the novice player can expect to produce a musical note at the desired pitch, instead of a whistle, screech or graunch. Jim Woodhouse and Paul Galluzzo explain why.