Content about “
genes

Article

Solving the genome puzzle

The human genome is represented by a sequence of 3 billion As, Cs, Gs, and Ts. With such large numbers, sequencing the entire genome of a complex organism isn't just a challenge in biochemistry. It's a logistical nightmare, which can only be solved with clever algorithms.
Article
cells

Modelling cell suicide

Martino Barenco and Mike Hubank shed light on suicidal cells and a mathematical model that could help fight cancer.

Article
mouse

Of pancakes, mice and men

Genes normally evolve by tiny mutations, but every now and then something more radical occurs and entire genes along a chromosome get flipped. Understanding gene flipping boils down to solving a problem from pure maths. Colva Roney-Dougal and Vincent Vatter explain, taking us on a journey from waiters sorting pancakes, via one of the richest men in the world, to the genetic similarities of mice and humans.

Article
monkey

Reconstructing the tree of life

Next year is a great one for biology. Not only will we celebrate 150 years since the publication of On the origin of species, but also 200 years since the birth of its author, Charles Darwin. At the heart of Darwin's theory of evolution lies a beautifully simple mathematical object: the evolutionary tree. In this article we look at how maths is used to reconstruct and understand it.