## Articles

The human genome is represented by a sequence of 3 billion As, Cs, Gs, and Ts. With such large numbers, sequencing the entire genome of a complex organism isn't just a challenge in biochemistry. It's a logistical nightmare, which can only be solved with clever algorithms.

"It's a match!" cries the CSI. At first glance it might seem that if the police have matched a suspect's DNA to evidence from the crime scene, then the case is closed. But some statistical thinking is required to understand exactly what a match is, and importantly, how juries should assess this as part of the evidence in a trial.

**Martino Barenco**and

**Mike Hubank**shed light on suicidal cells and a mathematical model that could help fight cancer.

**David Spiegelhalter** explains that waiting for an infinite number of monkeys to produce the complete works of Shakespeare is not just a probabilistic certainty, it also gives us an insight into how long we can expect to wait for a rare event to happen.

*x*

^{k}really the best one?

**Chris Sangwin**makes an interesting case that it is not.

*x*

^{k}? If you're up to speed with your calculus, you can probably rattle the answer off by heart. But can you prove it?

**Chris Sangwin**introduces an ingenious method for deriving the integral from first principles.

**Colva Roney-Dougal**and

**Vincent Vatter**explain, taking us on a journey from waiters sorting pancakes, via one of the richest men in the world, to the genetic similarities of mice and humans.