Articles

The human genome is represented by a sequence of 3 billion As, Cs, Gs, and Ts. With such large numbers, sequencing the entire genome of a complex organism isn't just a challenge in biochemistry. It's a logistical nightmare, which can only be solved with clever algorithms.

"It's a match!" cries the CSI. At first glance it might seem that if the police have matched a suspect's DNA to evidence from the crime scene, then the case is closed. But some statistical thinking is required to understand exactly what a match is, and importantly, how juries should assess this as part of the evidence in a trial.

Martino Barenco and Mike Hubank shed light on suicidal cells and a mathematical model that could help fight cancer.

David Spiegelhalter explains that waiting for an infinite number of monkeys to produce the complete works of Shakespeare is not just a probabilistic certainty, it also gives us an insight into how long we can expect to wait for a rare event to happen.
 

Coming to think of it, is the standard formula for the integral of xk really the best one? Chris Sangwin makes an interesting case that it is not.
What's the integral of xk? If you're up to speed with your calculus, you can probably rattle the answer off by heart. But can you prove it? Chris Sangwin introduces an ingenious method for deriving the integral from first principles.
Genes normally evolve by tiny mutations, but every now and then something more radical occurs and entire genes along a chromosome get flipped. Understanding gene flipping boils down to solving a problem from pure maths. Colva Roney-Dougal and Vincent Vatter explain, taking us on a journey from waiters sorting pancakes, via one of the richest men in the world, to the genetic similarities of mice and humans.