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  • Digital heart

    Living Proof: Building digital hearts

    19 November, 2025

    Imagine if your doctor had a digital model of your heart, personalised to you and updated with your latest medical information. This isn't science fiction – this revolutionary healthcare is being tested now. In this podcast we speak to Steven Niederer, who leads the CVDNet project developing and testing these ideas, and his colleague Richard Wilkinson, from the University of Nottingham.

    Richard is one of the organisers of the long research programme, Representing, calibrating & leveraging prediction uncertainty from statistics to machine learning (RCL), held earlier this year at the Isaac Newton Institute for the Mathematical Sciences (INI).

    We first spoke to Steven back in 2019 when he helped organise the Fickle Heart programme at the INI. In this podcast, Richard and Steven tell us about digital twins, digital hearts, and how the RCL programme and CVDNet build on the work started back in 2019 with the Fickle Heart programme.

    You can find out more about some of the ideas discussed in this podcast in these short introductions:

    • Maths in a Minute: Mathematical models
    • Maths in a Minute: Differential equations
    • Maths in Minute: Machine learning

    This content was produced as part of our collaborations with the Isaac Newton Institute for Mathematical Sciences (INI) and the Newton Gateway to Mathematics.

    The INI is an international research centre and our neighbour here on the University of Cambridge's maths campus. The Newton Gateway is the impact initiative of the INI, which engages with users of mathematics. You can find all the content from the collaboration here.

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    mathematical modelling
    medicine and health
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